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Hypoxia has also been shown to drive the accumulation of mitochondrial Akt, which phosphorylates PDK1 at Thr346, inactivates PDHC, and reinforces the Warburg phenotype, a hallmark of cisplatin resistance [132]

Targeting cardiac stem cell senescence to treat cardiac aging and disease

In many instances in the central nervous system, across different model organisms, astrocytes provide neurons with lactate as energetic support ( in vivo ( 3.3 The lipid shuttle Glial cells have also been proposed to serve retinal ganglion cells by transferring lipids, termed the lipid shuttle

IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses

TMRM signal was excited with a DPSS laser (56110 nm, laser power at 0.1) and detected at 566685 nm (red channel)