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Moreover, compared with estradiol, genistein was superior in preserving all stages of healthy follicles, enhancing GCs proliferation, and reducing the population of atretic follicles in -radiation-induced POF rats (Haddad et al., 2020)

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It receives raw materials and has to synthesise GSH from scratch, which is an energy-dependent process limited by cysteine availability and the rate-limiting enzyme gamma-glutamylcysteine synthetase