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Progression to end-stage kidney disease ESKD is due to interstitial fibrosis, tubular atrophy, collapsing glomeruli, and mesangial proliferation [9]

However, despite aggressive interventions, the median survival for glioma patients is merely about 14.6 months

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P.AlbieroM.MenegazzoL.BoscaroE.PagninE.IoriE.et al (2010)