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At the time of the switch, a subset of patients expressed concerns about the long-term impact that it would have on their condition management, and in an online survey many stated that they were dissatisfied with the level of care received

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The patients in whom we have observed less meaningful response tend to be those who have not addressed the foundation, who have unrealistic expectations, or who have other factors (significant sleep restriction, untreated metabolic comorbidities, chaotic eating patterns) that any pharmacological adjunct would struggle against