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Their research demonstrated that TSA markedly improved cardiac function in mice after MI (increasing LVEF and LVFS, decreasing LVEDV and LVESV), alleviated myocardial hypertrophy, fibrosis and cardiomyocyte apoptosis, and suppressed inflammatory responses in cardiac tissue (reducing TNF-, IL-1 and p-NF-B p65 expression) (170)

GHK-Cu is a small, positively charged molecule