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Compared to IV formulations, these SC formulations may have several advantages, such as faster administration, better tolerability (particularly by reducing infusion-related reactions), potential for fewer dosing errors, self-administration, and patient preference (Desai et al., 2023, Jackisch et al., 2015, Overton et al., 2021, Pivot, et al., 2014, Usmani et al., 2022)

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However, when ROS production becomes overwhelming, compensatory mechanisms are inadequate, and pathophysiological consequences occur

PMID 22240654