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10.1016/j.plantsci.2011.04.017 Plant Sci

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S-CMC has a thioether structure and in vitro cell-based studies suggest it may exert antioxidant effects by directly scavenging ROS [73] and preventing oxidative stress-induced GSH efflux from cells [74]

Questions to be resolved concern determining the effect of ULT on adverse health outcomes beyond acute gout, the duration of ULT, and the optimum serum urate target for reduction of symptoms, comorbidities and minimal harms (in addition to confirming the clinical efficacy and safety of the treat-to-target approach)