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Changes of the glutathione redox system during the weaning transition in piglets, in relation to small intestinal morphology and barrier function

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Vitamin C is used readily by the immune system, and studies have shown that within 24 hours of getting a cold, vitamin C levels within our immune cells significantly decline

The VSAC are a family of membrane proteins that mediate the passive transport of organic anions in response to changes in intracellular osmolarity (Jackson and Strange, Another mechanism that has been proposed as transporter is an ascorbate-glutamate hetero-exchange (Grnewald and Fillenz, Tissue distribution The organs with the highest concentration of ascorbate are the adrenal glands (550 mg/kg), the brain (140 mg/kg), the liver (125 mg/kg), and in terms of size, the skeletal muscle with a concentration of 35 mg/kg (Richelle et al., In order for ascorbate to be able to reach tissues, it must go through the endothelial barrier of each tissue

doi: 10.1146/annurev.iy.12.040194.005015 224 PiccaAGuerraFCalvaniRCoelho-JniorHJLandiFBernabeiRet al