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doi:10.1177/15648265080292S118

Studies reveal enhanced fatty acid oxidation, increased energy expenditure, and improved metabolic efficiency through direct NNMT inhibition, positioning it as breakthrough tool for investigating obesity mechanisms without appetite suppression

Some research protocols combine both approaches for maximum metabolic correction

Liver findings included lower liver weight, reduced triglyceride content and less severe histological features of steatosis and inflammatory-cell infiltration in treated mice