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To view a copy of this licence, visit About this article Cite this article Faria, A.M., Valerio, C.M., Barcellos, C.R

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454 The management of HLH focuses initially on controlling the excessive inflammatory response to halt disease progression, followed by addressing underlying immune deficiencies and managing the primary disorder to prevent recurrence

Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model