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Furthermore, SCFAs activate FFAR2/FFAR3 receptors to directly release cecal ACh, further reinforcing excitatory drive within the ENS ( 4.3.2 Vasoactive intestinal peptide Vasoactive intestinal peptide (VIP), predominantly secreted by neurons in the myenteric and submucosal plexuses of the ENS, serves as a pivotal neurotransmitter coordinating gastrointestinal functions through dual VPAC1/VPAC2 receptor signaling

They can be taken with or without food, though vilazodone in particular is recommended with food

39 These findings reveal that autophagic failure is central to AD pathogenesis

Poon HF, Hensley K, Thongboonkerd V, Merchant ML, Lynn BC, Pierce WM, et al

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