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Perhaps most significantly, not a single serious adverse event was attributed to AOD-9604 administration across the entire trial program

CD38-targeted immuno-PET of multiple myeloma: from xenograft models to first-in-human imaging

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Figure 3 3.5 Anti-CD38 therapy enriches for (exhausted) PD1- TEMRA cells Our earlier analysis on anti-PD1-treated NKTL patients suggests CD38+ TEM and TCM are most susceptible to depletion by Daratumumab treatment ( Figure 2 )

Using products that maintain defined ingredient ratios and undergo quality testing may help reduce variables that could influence experimental outcomes