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Cross-age comparisons show that the genetic structures of pediatric and elderly IBD exhibit a bipolar differentiation VEO-IBD has the heaviest genetic burden: more than one-third of those with onset before age 6 carry single-gene defects, IL-10R mutations can be cured through hematopoietic stem cell transplantation [203,204,205], NOD2 biallelic mutations often lead to stricturing CD and high surgery rates [206],and rare defects such as lipopolysaccharide-responsive beige-like anchor protein (LRBA) and syntaxin-binding protein 2 (STXBP2) are also frequently observed [206, 207]

We are thankful to Katya Sverdlov for coordinating the study

2001 Oct;25(10):1459-64

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In addition, the spectrum-dependent differences in the level of the amino acids listed above was also kept during the subsequent rewatering, which may influence many physiological and biochemical processes including the compensatory growth of wheat during recovery