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To test whether the ER buffers T INM , we created the genetically encoded, Ca-insensitive T INM biosensor amphipathic lipid-packing domain inside the nucleus (ALPIN)

Se observ una prdida de 1.9 kg y 0.9 kg en el grupo de tratamiento (15 mg/kg/da de L-Carnitina) y el control respectivamente, suponiendo pacientes con un peso de 70 kg se necesitan de ms de 1050 mg por da de L-Carnitina