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The optimal loading protocol design has been explored by Benson et al

The therapeutic potential of Nrf2 activators in asthma is further supported by the results of studies indicating that Nrf2 activation can suppress allergic lung inflammation by modulating the type 2 innate lymphoid cell response, which is crucial in the allergic immune response [107]

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Bupropion increases dopamine activity and POMC neuronal activation, thereby reducing appetite and increasing energy expenditure (54)

Blockade of IL-17 signaling pathway effectively reverses alcohol-associated hepatic injury and compulsive drinking behaviors in dependent mice [140, 235], suggesting therapeutic potential of inflammatory cytokine targeting along the brain-liver axis