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The putative COX-3 isoform may be a product of the same gene as COX-1 but with different protein characteristics, possibly because of alternative mRNA splicing or post-translational modification

But injections of hyaluronic acid might also be indicated in individuals with: Intolerance or contraindications to nonsteroidal anti-inflammatory drugs (NSAIDS) Patients who are poor surgical candidates Chondrocalcinosis Any type of cartilage injury Clinical evidence shows support for using intra-articular hyaluronic acid in individuals intolerant to NSAIDS and those wishing to defer or not willing to undergo surgery

instead, they thrive in consortia, where various interactions occur

I Two forms of one molecule GSH and GSSG, distinguished by a single bond