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Thats where NAD+ and GHK-Cu come in

Stimulation tests using clonidine, arginine, and L-dopa were performed in that order, using the algorithm shown in Fig

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The left ventricular ejection fraction (LVEF) was measured by means of transthoracic echocardiography using a Vevo 2100 (Visual Sonics) system with a 9-70 MHz linear array transducer (MS-550S, v4.5)