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Disclosure of interest: PC: Nothing to disclose

Sub is a weird drug: a web-based study of lay attitudes about use of buprenorphine to self-treat opioid withdrawal symptoms

Generally, hydrophilic peptides dissolve well in water or saline, while hydrophobic peptides may require initial dissolution in a small amount of organic solvent (like DMSO or acetic acid) followed by dilution with aqueous buffer

For those considering AOD-9604, its important to manage expectationsit is not a magic weight-loss solution but can be a helpful fat-burning tool when combined with a proper diet and exercise regimen

Conventional Treatment : Short-term hypnotics or CBT-I