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Since the NNMT inhibitor 5-amino-1MQ significantly reduced intracellular 1-MNA concentrations, we hypothesized that NNMT inhibition in adipocytes would increase intracellular concentrations of the co-substrates NA and SAM and shunt more NA into the NAD+ salvage cycle

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Jose S., Hughbanks M.L., Binder B.Y.K., Ingavle G.C., Leach J.K

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