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Not enough B12 is a cause of fatigue, poor cognitive function, and is linked to increased cancer risk

Research indicates it can normalize circadian melatonin production patterns that become dysregulated with aging, potentially through effects on pineal gene expression and enzyme activities involved in melatonin synthesis

Accordingly, we obtained and analysed metabolite and transcript profiles of orthotopic lung tumours using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) and high-throughput RNA sequencing, respectively