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BersukerKHendricksJMLiZMagtanongLFordBTangPHet alThe CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

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However, complete inactivation of monophenolase activity in jr PPO1-wt was achieved only when both activity controller residues were mutated (Asn240Lys/Leu244Arg and Asn240Thr/Leu244Arg)