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Although most studies have not looked at a causative link between GI abnormalities and mitochondrial function, given the fact that mitochondrial dysfunction can cause GI abnormalities, including gastric dysmotility, hepatic and pancreatic dysfunction, and abnormalities in enterocyte function, it is possible that mitochondrial dysfunction is the primary abnormality leading to the GI dysfunction associated with these exposures

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Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis