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Johnson OL, Washington C, Davis SS et al

Oxidative stress and accelerated aging are the clearest targets, since glutathione is the front-line molecule that neutralizes free radicals before they damage mitochondria and DNA

10.1002/jps.23203 217 WeberS.ZimmerA.PardeikeJ

& Roden, M

These models highlight distinct pathological and temporal features of AD, including early synaptic changes and amyloid accumulation, providing valuable tools for studying disease progression and potential therapeutic targets