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Interfaces 16 , 1463314644 (2024)

Nature 491:364373 Schulte ML, Fu A, Zhao P et al (2018) Pharmacological blockade of ASCT2-dependent glutamine transport leads to anti-tumor efficacy in preclinical models

The SYBR Green Pro Taq HS premix qPCR assay kit from Accurate Biotechnology Co., Ltd was used for reverse transcription of total RNA

This fragmentation slows hypothesis generation, delays mechanistic validation, and weakens the iterative bench-to-bedside process needed to translate molecular findings into meaningful clinical outcomes

Shift Away from Dopaminergic Drugs: The AASM advises against the routine use of levodopa, pramipexole, and similar medications, due to evidence linking these drugs to the worsening of RLS symptoms over time