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What makes GLP-1 receptor agonists particularly interesting is their multifaceted mechanism of action

N.MartynyukN.WijeyekoonR.et al (2016)

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Progressive reduction of ATP availability occurs with increasing age, due to the long- term accumulation within the otherwise wild-type mtDNA complement of ROS-damaged mtDNA which remains replicable but translates to incompetent or poorly competent mitochondria

Asked recently whether the molecule is even what the original team believed it was, one of Sikirics collaborators told Undark, As long as it works and has no side effects, who cares? If you read my work, you know Im not big for pathophysiology