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Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle

Accordingly, the pleiotropic mechanisms of antioxidants-including mitigation of oxidative damage, modulation of immune responses, and support of neural repair pathways observed in preclinical models provide a strong rationale for investigating them as potential disease-modifying strategies in MS

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2021;72:e876e880

Gene aberration profile of tumors of adolescent and young adult females