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10.1016/j.prp.2025.156297 118 YaoX.SunK.YuS.LuoJ.GuoJ.LinJ.et al (2021)

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In this regard, increased loss of glutathione may change the intracellular environment to a prooxidant state and thereby caused prominent changes in gene expression, which is ultimately evolving into a malignant state [26]

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Thus, glutathionylation of roGFP2 WT -PfGrx C32S/C88S by GSSG was about 2.5-times faster as the previously determined second-order rate constant for the glutathionylation of PfGrx C32S/C88S by GSSCys (Table 1) 14