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The Use of Traditional Chinese Medicine in Relieving EGFR-TKI-Associated Diarrhea based on Network Pharmacology and Data Mining

Bruning U, Morales-Rodriguez F, Kalucka J, Goveia J, Taverna F, Queiroz KCS, et al

The immunosuppressive Treg and MDSC are increased by VEGF and it induces macrophage polarization toward an M2 phenotype while decreasing LT-CD8 + and LT-CD4 +

The role of the intestinal mycobiota is under investigation, and the importance of the fungal fraction of the gut can be demonstrated in IBD by a CD biomarker ASCA antibody (anti- Saccharomyces cerevisiae )

In the model cytosolic GSH has three fates: it is transported into the blood, there is a net flux to GSSG, and 0.2% is removed per hour corresponding to detoxification reactions and excretion into the bile