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BMSCs modulate the CD40/CD40L pathway to influence iron homeostasis and lanosterol synthesis in MM cells, driving ROS accumulation and ferroptosis ( A recent study revealed that mitochondrial metabolic kinase PCK2 phosphorylates and activates ACSL4, driving phospholipid remodeling linked to ferroptosis

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This participant did not continue into phase 2 so that she could pursue private treatment

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