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Rating: 4.378 (11 reviews)

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Description

Laschinger, M

Noutoshi Y, Ito T, Seki M, Nakashita H, Yoshida S, Marco Y, Shirasu K, Shinozaki K

The presence of high concentrations of reduced thioredoxin in a trr1 mutant is unexpected

Key review articles encapsulate the skepticism towards the ANLS hypothesis, arguing that the stoichiometric requirements, kinetics of lactate transport, and in vivo metabolic data do not support a major role for lactate shuttling in meeting neuronal energy demands during activation (Dienel, 2012, 2017, 2019)

Funding This review was funded by: the European Regional Development Fund (ERDF) through the Operational Programme for Competitiveness and Internationalisation (COMPETE 2020) and Portuguese national funds via Fundao para a Cincia e a Tecnologia (FCT), under projects UIDB/04539/2020, UIDP/04539/2020, and LA/P/0058/2020