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Proceedings of the National Academy of Sciences 2021

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Nrf2 plays a critical role in maintaining cellular function and viability, particularly during stress

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This combination therapy may inhibit tumor cell epithelial-mesenchymal transition via blocking CXCR2/TGF--mediated PI3K/Akt/GSK-3/Snail signaling pathway, suggesting potential for clinical trials in lung cancer patients [177]

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