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Metabolic reprogramming for cancer cells and their microenvironment: beyond the Warburg effect

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Unlike other cell death pathways, ferroptosis involves the accumulation of oxidized lipids in cell membranes, which GPx4 counters by directly reducing these hydroperoxides to stable alcohols

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J Proteome Res 20:45534565

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Senescent cells are those that have stopped dividing and dont go through the normal process of cell death, so they can accumulate

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