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Angiopoietin-1 is reported to prevent H 2 O 2 -induced glomerular endothelial cells by the ERK1/2 pathway [58]

2.2 Hydrophobicity Hydrophilic surfaces tend to exhibit better dispersion in aqueous media, while hydrophobic-surfaced nanoparticles tend to aggregate due to their tendency to minimize contact with water molecules, which can lead to reduced stability and poor dispersion in biological fluids

Dysregulation of this pathway contributes to insulin resistance, chronic inflammation, and metabolic dysfunction, which are hallmark features of metabolic syndrome (Hopkins et al., 2020)

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