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Joshua Kritzer, an associate professor of chemistry at Tufts University, says the study offers evidence that the stapled peptide approach is worth pursuing and could lead to new drugs that interfere with specific protein interactions

Suzuki T, Yazaki Y, Voors AA, et al

Int Immunopharmacol 2020;85:106646.ArticlePubMed 165

"In brief: The innate and adaptive immune systems"

Mechanistically, glutamine limitation decreases GSH levels and sarco/endoplasmic reticulum Ca 2+ -ATPase (SERCA) glutathionylation, resulting in reduced SERCA activity 58