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The high-risk groups include: Pregnant women, due to increased folate requirements for fetal development Individuals with a diet lacking in folate-rich foods, such as leafy greens and legumes Those with alcohol dependence, as alcohol interferes with folate absorption Patients with malabsorption conditions, such as celiac disease Individuals taking certain medications, such as anticonvulsants and methotrexate Screening for folate deficiency is key for pregnant women

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Further, the histopathology data (Fig

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