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During autooxidation of glucose, enzymatic pathways, such as the NOX pathway, become the main sources of ROS 38,39

The underlying molecular mechanisms involve direct ROS-induced oxidative damage to neuronal lipids, proteins and DNA [331], as well as ROS-mediated oxidative modifications that crucially promote the aberrant aggregation of toxic proteins [332]

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Besides reducing -amyloid load, treatment with DFMO coerced astrocytes into a neuroprotective state

Prevalence and stats for thyroid problems The prevalence of thyroid diseases varies depending on many factors including age, gender, and geographical area, Fig