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Partial correlation analysis between metabolites revealed that MET, TYR, and TRP formed a tight cluster of interacting molecules in these MDD patients

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doi: 10.9778/cmajo.20170070 [DOI] [PMC free article] [PubMed] [Google Scholar] Karan L, Makenov M, Kolyasnikova N, Stukolova O, Toporkova M, and Olenkova O (2018)

In the mevalonate pathway, the enzyme 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase, which converts HMG-CoA into mevalonate, is common to the biosynthetic pathways of both coenzyme Q 10 and cholesterol and is inhibited by statins (cholesterol-lowering drugs