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10.1073/pnas.1815150116 20 AyaA

Sevak et al

Kasperczyk S, Kasperczyk A, Ostawska A, et al

41 Ketamine can cause a transient significant decrease in intracellular calcium, resulting in a negative inotropic effect

In accordance with this, we have detected abnormal SOD1 oligomers crosslinked via intermolecular disulfide bonds in spinal cord of SOD1 -ALS cases as well as transgenic mice expressing human SOD1 with ALS mutations (G37R, G93A, and L126Z) [31, 102]