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For all procedures, find buffer compositions in Supplemental Table 1

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Furthermore, increased expression of heme oxygenase-1 (HO-1) in microglia and loss of copper chaperone protein (CP) activity in astrocytes contribute to iron deposition in the central nervous system (CNS) and neuronal death [182]

A Revisit to the Natural History of Homocystinuria Due to Cystathionine -Synthase Deficiency. Molecular Genetics and Metabolism, vol

-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategies