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Anti-inflammatory effects of astroglial 7 nicotinic acetylcholine receptors are mediated by inhibition of the NF-B pathway and activation of the Nrf2 pathway

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Glucose enters the cellular milieu through glucose transporter 1 (Glut-1), followed by conversion to pyruvate, which is mediated by a series of enzymatic steps, including glucose phosphorylation to glucose-6-phosphate (G-6-P), followed by conversion to pyruvate, reducing NAD + to NADH and generating ATP molecules via oxidative phosphorylation (OXPHOS) through the mitochondrial electron transport chain (ETC)

10.1097/MD.0000000000038875 44 YanJ