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Although small randomized trials and prospective registries report angiographic stabilization or regression and low event rates, adequately powered multicenter trials evaluating a whole-food plant-based diet as a standalone primary therapy for stable CAD are lacking

Use multiple timepoints to capture progression, standardize assays and scoring criteria, and prespecify primary and secondary endpoints to guide analysis and reduce selective reporting

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SuperScript IV reverse transcriptase (Invitrogen) was used for cDNA synthesis and for transcript sequencing reactions, which used a 2:1 ratio of dNTPs to ddNTPs