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Conversely, and interestingly, UGTs present in the bladder can protect against accumulation of toxins since they are highly expressed on the surface of bladder tissue, particularly in females where it is postulated that the lower incidence of bladder cancer is related to increased UGT isoform activity

Reserve concomitant prescribing of acetaminophen and codeine phosphate tablets and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate [see Warnings, Drug Interactions]

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World J Gastroenterol 20(10):26532663

Consistent zinc intake can help create a smoother, more even complexion, particularly for those prone to post-inflammatory hyperpigmentation