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The classical metastatic cascade starts from a primary, epithelial, neoplastic lesion and includes: (1) epithelial mesenchymal transition (EMT) with a breach of the basement membrane barrier

Suited for researchers investigating multi-pathway regenerative signalling in musculoskeletal, vascular, or neurological models

Wang S, Liu Y, Sun Q, Zeng B, Liu C, Gong L, Wu H, Chen L, Jin M, Guo J, et al

Fam.Cancer 4 , 1316 (2005)

A double-blind randomized placebo-controlled trial found that amifostine (740 mg/m 2 ) improved the sensory neuropathy induced by platinum/taxane-based treatment of ovarian cancer, but there was almost no difference in specific sensory or motor symptoms of self-estimation [150]