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and into the roles that melanocytes and melanin play in the maintenance of homeostasis of the oral mucosa, as well as into the roles physiological or benign oral mucosal melanin hyperpigmentations may play as precursors of premalignant and malignant oral melanotic lesions

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Consequence: increased eumelanin synthesis documented in the B16-F10 and MNT-1 cell models

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Melanoma Melanosis is a skin condition of abnormal or excessive accumulation of pigment in the skin