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Why it matters: Many people are unknowingly B12 deficientespecially those under stress, plant-based diets, digestive issues, or frequent travel

Nitric oxide (NO) plays a multifaceted role in CRC, acting as both a promoter and an inhibitor of cancer progression depending on its concentration, timing, and cellular context

(iv) optimal Se status (100 nm/l in cell culture) is critical for alternative macrophage activation, leading to attenuated expression of proinflammatory mediators (Reference Nelson, Lei and Prabhu57)