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The STAT3 pathway, when improperly regulated, amplifies inflammatory cascade reactions by upregulating key genes responsible for Th17 cell differentiation, a primary driver of tissue damage in inflammatory bowel disease

Yu et al., 2004)

8, e24005

Charpak-Amikam, Y

However, subsequent studies have indicated that nec-1 could potentially inhibit ferroptosis and that ferroptosis might be more significant than necroptosis in renal IRI [18, 36]