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Thus, we concluded that GD-mediated sequential phosphorylation of SIRT7 by AMPK and GSK3 facilitates its binding to SKP2, which prevents SKP2 S256 phosphorylation by AMPK

Booker LA, et al

2020 May;24(9):4967-4980

G.WintG

Drugs currently used in PC therapy frequently induce resistance and PC progresses toward metastatic castration-resistant forms (mCRPC), making it virtually incurable