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The bronchodilator bambuterol, a dimethylcarbamate prodrug of terbutaline (Figure 12), has a significantly reduced first-pass metabolic effect due to the protection of the metabolically susceptible phenolic hydroxyl group in the drug structure

Pancreatitis was reported as a rare serious adverse event in clinical trials

In our previous study, pegylated arginase I treatment may reduce OTC protein expression in human T-ALL cell lines and also hMSCs [153]

While these results are highly concordant with our findings in the N1IC glioma cells, which harbor an astrocyte-like phenotype and are highly sensitive to RSL3-induced ferroptosis, we wanted to know whether the RSL3-sensitive cells in human gliomas bore a metabolic resemblance to N1IC glioma cells

First, yeast is separated from the broth by centrifugation using disc-stack centrifuges and washed to remove any residual medium