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Hyperactivated innate immune responses, dysregulation of ACE2 expression and its downstream pathway may be possible mechanisms

Elaboration: While Spirulina is recognized for its nutritional and therapeutic potential, the specific mechanisms of action for many of its health benefits are not fully understood

Melasma (also referred to as chloasma or the mask of pregnancy) is a common, acquired cutaneous pigmentary condition that results in mostly symmetrical, brownish pigmentation that affects the face and occasionally the forearms and back (Figure 1A)