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CO2 laser skin resurfacing can cause some discomfort during the procedure, but most patients report that the pain is manageable

Glutathione is a powerful antioxidant that protects cellular components against oxidative stress

Some endogenous and synthetic antioxidants, such as polyethylene glycol absorbed (PEGSOD), tirilizad (Upjohn), and vitamin E, have been studied for antioxidant effects, but none have shown therapeutic effects (Hawryluk and Bullock, 2015)

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Cancer Res 54 : 55315534 Karnieli E, Werner H, Rauscher II FJ, Benjamin LE, LeRoith D (1996) The IGF-I receptor gene promoter is a molecular target for the Ewing's sarcoma-Wilms' tumor 1 fusion protein